Dr Victoria McAneany from the RSCI, Dublin will deliver a seminar on her research entitled "Rapid Actions of Aldosterone in the Renal Cortical Collecting Duct -From Receptor to Effector”
PhD studentship available
Applications are invited from enthusiastic Life Science graduates to join a dynamic team focused on investigating the mechanisms underlying the control of smooth muscle. Based in state of the art laboratories at DkIT, the successful candidate will have the opportunity to receive training in electrophysiology, molecular biology, Ca2+ imaging and immunohistochemistry.
Urinary incontinence is a distressing condition characterised by involuntary leakage of urine from the bladder. In healthy individuals this is prevented by contraction of smooth muscle in the urethra, though the mechanisms by which this is achieved are unclear. However, there is now a body of evidence which suggests that contraction of the urethra is regulated by the electrical activity of a population of specialized pacemaker cells, termed Interstitial Cells of Cajal (ICC).
The aim of this study is to use a murine model to test the hypothesis that urethral ICC act as specialised pacemaker cells.
The ideal applicant should have an Honours degree in Physiology or a related subject and have demonstrated an aptitude for research during the course of their undergraduates studies. A stipend of €12,500 per annum is available and fees are paid in full. The successful applicant will be based in the Smooth Muscle Research Centre's state of the art laboratories and receive thorough training in electrophysiology (patch clamp), cell dispersal, Ca2+ imaging and molecular biological techniques.
Applicants should send a full CV (including 2 referees) to mark.hollywood@dkit.ie or gerard.sergeant@dkit.ie.